Glucagon-like peptide-1 (GLP-1) is a hormone that regulates blood sugar, appetite, and digestion. Synthetic versions of GLP-1, called GLP-1 agonists, are used as medications to treat type 2 diabetes and obesity:
How they work
GLP-1 agonists mimic the effects of GLP-1 by:
Stimulating the pancreas to release insulin
Slowing down how quickly food leaves the stomach
Increasing feelings of fullness
Other benefits
GLP-1 agonists may also:
Lower blood pressure
Improve lipid disorders
Improve fatty liver disease
Reduce the risk of heart disease and kidney disease
Some examples of GLP-1 agonists include Trulicity, Ozempic, Rybelsus, and Wegovy.
Side effects of GLP-1 agonists include:
“Ozempic face”, which can include a hollowed look to the face, changes in the size of the lips, cheeks, and chin, wrinkles on the face, sunken eyes, and sagging jowls around the jaw and neck
The FDA recommends that patients obtain a prescription from their doctor and fill it at a state-licensed pharmacy.
A closer look at Ozempic, Wegovy and other GLP1 medications for Weight Loss
A closer look at Ozempic, Wegovy and other GLP1 medications Below is a summary of the most important GLP-1 drugs, including Ozempic, Wegovy and others, with emphasis on their indications, results, dosing, adverse effects, and costs. Ozempic (Semaglutide) Primary Use:...
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